-
The power of disruptive technological innovation: Transcatheter aortic valve implantation.
February 6, 2015 Editor 0
Related Articles The power of disruptive technological innovation: Transcatheter aortic valve implantation.
J Biomed Mater Res B Appl Biomater. 2014 Dec 24;
Authors: Berlin DB, Davidson MJ, Schoen FJ
Abstract
We sought to evaluate the principles of disruptive innovation, defined as technology innovation that fundamentally shifts performance and utility metrics, as applied to transcatheter aortic valve implantation (TAVI). In particular, we considered implantation procedure, device design, cost, and patient population. Generally cheaper and lower performing, classical disruptive innovations are first commercialized in insignificant markets, promise lower margins, and often parasitize existing usage, representing unattractive investments for established market participants. However, despite presently high unit cost, TAVI is less invasive, treats a “new,” generally high risk, patient population, and is generally done by a multidisciplinary integrated heart team. Moreover, at least in the short-term TAVI has not been lower-performing than open surgical aortic valve replacement in high-risk patients. We conclude that TAVI extends the paradigm of disruptive innovation and represents an attractive commercial opportunity space. Moreover, should the long-term performance and durability of TAVI approach that of conventional prostheses, TAVI will be an increasingly attractive commercial opportunity. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2014.
PMID: 25545639 [PubMed – as supplied by publisher]
7 Aspirations for Better ICT4D in 2015 Democratizing biotech research
