Molecular diversity of Chickpea chlorotic dwarf virus in Sudan: high rates of intra-species recombination – a driving force in the emergence of new strains.
September 4, 2015 Editor 0
Infect Genet Evol. 2015 Jan;29:203-15
Authors: Kraberger S, Kumari SG, Hamed AA, Gronenborn B, Thomas JE, Sharman M, Harkins GW, Muhire BM, Martin DP, Varsani A
In Sudan Chickpea chlorotic dwarf virus (CpCDV, genus Mastrevirus, family Geminiviridae) is an important pathogen of pulses that are grown both for local consumption, and for export. Although a few studies have characterised CpCDV genomes from countries in the Middle East, Africa and the Indian subcontinent, little is known about CpCDV diversity in any of the major chickpea production areas in these regions. Here we analyse the diversity of 146 CpCDV isolates characterised from pulses collected across the chickpea growing regions of Sudan. Although we find that seven of the twelve known CpCDV strains are present within the country, strain CpCDV-H alone accounted for ∼73% of the infections analysed. Additionally we identified four new strains (CpCDV-M, -N, -O and -P) and show that recombination has played a significant role in the diversification of CpCDV, at least in this region. Accounting for observed recombination events, we use the large amounts of data generated here to compare patterns of natural selection within protein coding regions of CpCDV and other dicot-infecting mastrevirus species.
PMID: 25444941 [PubMed – indexed for MEDLINE]
- Quotable: Internet for the next 5 billion people
- Entrepreneurship education in Sudan
- Genetic differentiation analysis for the identification of complementary parental pools for sorghum hybrid breeding in Ethiopia.
- Sporadic mutations may be responsible for half of schizophrenia cases
- Good laboratory practices guarantee biosafety in the Sierra Leone-China friendship biosafety laboratory.
- The Role of Public Knowledge, Resources, and Innovation in Responding to the Ebola Outbreak.
Assessing scale-up of mHealth innovations based on intervention complexity: two case studies of child health programs in Malawi and Zambia. How Refugee Saharawis Use ICTs in Their Fight for Independence
Subscribe to our stories
- 9 Best Practices for Cleaning, Managing, and Tagging Your Data August 30, 2017
- Empowering agricultural extension agents to deliver improved farming technologies August 30, 2017
- Our Experiment Using Facebook Chatbots to Improve Humanitarian Assistance August 30, 2017
- Yes, Girls Can Code Software in Zambia! August 30, 2017
- A Novel Analysis of Mobile Phone Impact on Rural Farmers August 30, 2017